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Abstract BACKGROUND: Hypertension increases the risk of left ventricular (LV) diastolic dysfunction, and anti-hypertensive therapy may improve LV relaxation. The aim of this study was to investigate whether combining an angiotensin-receptor blocker (ARB) with either hydrochlorothiazide (HCTZ) or a calcium-channel blocker (CCB) improves LV relaxation in patients with hypertension and diastolic dysfunction.Methods?and?Results:Hypertensive patients who had not achieved their target blood pressure with at least 4 weeks of ARB therapy were randomly assigned to receive either

Abstract BACKGROUND: There is growing evidence that hypertensive disorders of pregnancy are associated with increased long term cardiovascular mortality in the mother. However, hypertension in pregnancy, until recently, has been largely ignored as a risk factor for future cardiovascular disease and mortality, as the link between the two is not fully understood. OBJECTIVE: To determine the association between women with hypertension in pregnancy and long term cardiovascular disease mortality. STUDY DESIGN: All women who delivered

Objective To compare hypertensive patients with and without chronic kidney disease and identify factors associated with their clinical condition and antihypertensive treatment. Method This was a cross-sectional study conducted with patients hospitalized in a general medical ward at a university hospital in the city of S?o Paulo, Brazil. Data were collected from medical records. Significance was set at p<0.05. Results Of the 386 patients studied, 59.3% presented hypertension and, of these, 37.5% presented chronic kidney

Abstract IMPORTANCE: The association between obesity and diabetic retinopathy (DR) is equivocal, possibly owing to the strong interrelation between generalized and abdominal obesity leading to a mutually confounding effect. To our knowledge, no study in Asia has investigated the independent associations of these 2 parameters with DR to date. OBJECTIVE: To investigate the associations of generalized (defined by body mass index [BMI], calculated as weight in kilograms divided by height in meters squared) and abdominal

Abstract BACKGROUND: Due to the importance of coronary artery disease (CAD), continuous investigation of the risk factors (RFs) is needed. OBJECTIVE: To evaluate the prevalence of RFs for CAD in cities in Rio Grande do Sul State, and compare it with that reported in a similar study conducted in the same cities in 2002. METHODS: Cross-sectional study on 1,056 healthy adults, investigating the prevalence and absolute and relative frequencies of the following RFs for CAD: